Author: Braeuer, M.    [Bräuer, M.]
Paper Title Page
THPOMS007 Beam Diagnostics for FLASH RT in the Varian ProBeam System 2951
 
  • M. Schedler, S. Busold
    VMS-PT, Troisdorf, Germany
  • M. Bräuer
    Siemens Med, Erlangen, Germany
 
  FLASH RT is a novel ultra-high dose rate radiation therapy technique with the potential of sparing radiation induced damages to healthy tissue while keeping tumor control unchanged. Recent studies indicate that this so-called FLASH effect occurs when applying high doses of several Grays in a fraction of a second only, and thus significantly faster than with conventionally available radiation therapy systems today. Varian’s ProBeam system has been enabled to deliver ultra-high beam currents for FLASH treatments at 250 MeV beam energy. The first clinical trial is currently conducted at Cincinnati Children’s Hospital Medical Center and all involved human patients have been successfully irradiated at FLASH dose rates, operating the system at cw cyclotron beam currents of up to 400 nA. With these modifications, treatment times could be reduced down to less than a second. First automated switching between conventional and FLASH operation modes has been demonstrated in non-clinical environment, including switching of the dose monitor system characteristics and all involved beam diagnostics. Furthermore, for an improved online beam current control system with full control over dose rate in addition to dose Varian has demonstrated first promising results that may improve future applications.  
DOI • reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2022-THPOMS007  
About • Received ※ 07 June 2022 — Revised ※ 15 June 2022 — Accepted ※ 16 June 2022 — Issue date ※ 04 July 2022
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