JACoW is a publisher in Geneva, Switzerland that publishes the proceedings of accelerator conferences held around the world by an international collaboration of editors.
@inproceedings{schedler:ipac2022-thpoms007,
author = {M. Schedler and M. Bräuer and S. Busold},
title = {{Beam Diagnostics for FLASH RT in the Varian ProBeam System}},
booktitle = {Proc. IPAC'22},
% booktitle = {Proc. 13th International Particle Accelerator Conference (IPAC'22)},
pages = {2951--2953},
eid = {THPOMS007},
language = {english},
keywords = {controls, radiation, proton, operation, target},
venue = {Bangkok, Thailand},
series = {International Particle Accelerator Conference},
number = {13},
publisher = {JACoW Publishing, Geneva, Switzerland},
month = {07},
year = {2022},
issn = {2673-5490},
isbn = {978-3-95450-227-1},
doi = {10.18429/JACoW-IPAC2022-THPOMS007},
url = {https://jacow.org/ipac2022/papers/thpoms007.pdf},
abstract = {{FLASH RT is a novel ultra-high dose rate radiation therapy technique with the potential of sparing radiation induced damages to healthy tissue while keeping tumor control unchanged. Recent studies indicate that this so-called FLASH effect occurs when applying high doses of several Grays in a fraction of a second only, and thus significantly faster than with conventionally available radiation therapy systems today. Varian’s ProBeam system has been enabled to deliver ultra-high beam currents for FLASH treatments at 250 MeV beam energy. The first clinical trial is currently conducted at Cincinnati Children’s Hospital Medical Center and all involved human patients have been successfully irradiated at FLASH dose rates, operating the system at cw cyclotron beam currents of up to 400 nA. With these modifications, treatment times could be reduced down to less than a second. First automated switching between conventional and FLASH operation modes has been demonstrated in non-clinical environment, including switching of the dose monitor system characteristics and all involved beam diagnostics. Furthermore, for an improved online beam current control system with full control over dose rate in addition to dose Varian has demonstrated first promising results that may improve future applications.}},
}