JACoW is a publisher in Geneva, Switzerland that publishes the proceedings of accelerator conferences held around the world by an international collaboration of editors.
TY - CONF AU - Kongmali, K. AU - Apiwattanakul, P. AU - Jitvisate, M. AU - Kangrang, N. AU - Lithanatudom, P. AU - Rimjaem, S. AU - Saisut, J. AU - Thongbai, C. ED - Zimmermann, Frank ED - Tanaka, Hitoshi ED - Sudmuang, Porntip ED - Klysubun, Prapong ED - Sunwong, Prapaiwan ED - Chanwattana, Thakonwat ED - Petit-Jean-Genaz, Christine ED - Schaa, Volker R.W. TI - Progress on Electron Beam Optimization for FLASH Radiotherapy Experiment at Chiang Mai University J2 - Proc. of IPAC2022, Bangkok, Thailand, 12-17 June 2022 CY - Bangkok, Thailand T2 - International Particle Accelerator Conference T3 - 13 LA - english AB - At present, one of diseases that kills many people worldwide is cancer. The FLASH radiotherapy (RT) is a promising cancer treatment under study. It involves the fast delivery of RT at much higher dose rates than those currently used in clinical practice. The very short time of exposure leads to the destruction of the cancer cells, while the nearby normal cells are less damaged as compared with conventional RT. This work focuses on study of FLASH-RT experiment using electron beams produced from the accelerator system at the PBP-CMU Electron Linac Laboratory. The structure and properties of our electron pulses with microbunches in picosecond time scale and macropulses in microsecond time scale match well to FLASH-RT requirement. To optimize the condition for experiment, the electron beam simulations are performed by varying energy, charge and bunch length. The 25 MeV electrons energy before hitting the window for 50 and 100 pC bunch length have a bunch length of 1.16 and 1.97 ps. The transverse rms beam sizes of 50 pC and 100 pC bunch charges have the differences between ASTRA and GEANT4 from 7.90 % to 34.0 %. The optimized electron beam properties from this study will be used as the guideline for further simulation and experiment preparation. PB - JACoW Publishing CP - Geneva, Switzerland SP - 2146 EP - 2149 KW - electron KW - simulation KW - experiment KW - radiation KW - linac DA - 2022/07 PY - 2022 SN - 2673-5490 SN - 978-3-95450-227-1 DO - doi:10.18429/JACoW-IPAC2022-WEPOTK036 UR - https://jacow.org/ipac2022/papers/wepotk036.pdf ER -