JACoW is a publisher in Geneva, Switzerland that publishes the proceedings of accelerator conferences held around the world by an international collaboration of editors.
TY - CONF AU - Apiwattanakul, P. AU - Lithanatudom, P. AU - Nimmanpipug, P. AU - Phueng-ngern, C. AU - Rimjaem, S. AU - Saisut, J. ED - Zimmermann, Frank ED - Tanaka, Hitoshi ED - Sudmuang, Porntip ED - Klysubun, Prapong ED - Sunwong, Prapaiwan ED - Chanwattana, Thakonwat ED - Petit-Jean-Genaz, Christine ED - Schaa, Volker R.W. TI - Monte Carlo Simulation of Electron Beam in Phantom Water for Radiotherapy Application J2 - Proc. of IPAC2022, Bangkok, Thailand, 12-17 June 2022 CY - Bangkok, Thailand T2 - International Particle Accelerator Conference T3 - 13 LA - english AB - Radiotherapy (RT) is an effective treatment that can control the growth of cancer cells. There is a hypothesis suggests that secondary electrons with an energy of a few eV produced from RT play an important role on cancer’s DNA strand break. In this study, the Monte Carlo simulation of electron beam irradiation in phantom water is performed to investigate the production of low-energy electrons. Electron beams produced from an radio-frequency linear accelerator (RF linac) are used in this study. The accelerator can generate the electron beam with adjustable energy of up to 4 MeV and adjustable repetition rate of up to 200 Hz. With these properties, the electron dose can be varied. We used ASTRA software to simulate the electron beam dynamics in the accelerator and GEANT4 toolkit for studying interactions of electrons in water. The energy of electrons decreases from MeV scale to keV-eV scale as they travel in the water. From simulations, the dose distribution and depth in phantom water were obtained for the electron dose of 1, 3, 5, 10, 25, and 50 Gy. Further study on effect of low-energy electron beam with these dose values on cancer DNAs will be performed with GEANT4-DNA simulation. PB - JACoW Publishing CP - Geneva, Switzerland SP - 3011 EP - 3013 KW - electron KW - simulation KW - radiation KW - photon KW - linac DA - 2022/07 PY - 2022 SN - 2673-5490 SN - 978-3-95450-227-1 DO - doi:10.18429/JACoW-IPAC2022-THPOMS026 UR - https://jacow.org/ipac2022/papers/thpoms026.pdf ER -